Bioinformatics

Bioinformatics and computational biology involve the use of techniques from
applied mathematics,
informatics,
statistics, and
computer science to solve biological problems.
Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.
The terms
bioinformatics and
computational biology are often used interchangeably, although the former typically focuses on
algorithm development and specific computational methods, while the latter focuses more on
hypothesis testing and discovery in the biological domain.